Street Scene is an American opera by Kurt Weill (music), Langston Hughes (lyrics), and Elmer Rice (book). Written in 1946 and premiered in Philadelphia that year, Street Scene is based on the Pulitzer Prize-winning 1929 play of the same name by Rice.

It was Weill who referred to the piece as an "American opera", intending it as a groundbreaking synthesis of European traditional opera and American musical theater. He received the first Tony Award for Best Original Score for his work, after the Broadway premiere in 1947. Considered far more an opera than a musical, Street Scene is regularly produced by professional opera companies and has never been revived on Broadway. Musically and culturally, even dramatically, the work inhabits the mid-ground between Weill's Threepenny Opera (1928) and Leonard Bernstein's West Side Story (1957).

The score contains operatic arias and ensembles, some of them, such as Anna Maurrant's "Somehow I Never Could Believe" and Frank Maurrant's "Let Things Be Like They Always Was," with links and references to the style of Giacomo Puccini. It also has jazz and blues influences, in "I Got a Marble and a Star" and "Lonely House". Some of the more Broadway-style musical numbers are "Wrapped In a Ribbon and Tied In a Bow", "Wouldn't You Like To Be On Broadway?" and "Moon-faced, Starry-eyed", an extended song-and-dance sequence. Benny Goodman and His Orchestra recorded "Moon-Faced, Starry-Eyed" with Johnny Mercer on the vocal in 1947. It was also recorded by the jazz vocal group The Hi-Lo's.