Queenie Pie is an unfinished opera by American jazz musician Duke Ellington. It tells a story of a Harlem beautician named Queenie Pie. Ellington referred to the opera as "opera comique", and worked on it from the 1930s until his death in 1974. The opera was later staged in 1986, but the arrangements were lost. In 2007 musician Marc Bolin recreated the opera that was staged in the Oakland Opera Theater.

The opera is about Queenie Pie, a black beautician named best in town, who is challenged by a lighter-skinned woman, Café O'Lay. Queenie's manager and lover, Holt Faye, falls in love with O'Lay, but she shoots and kills him in a quarrel. Queenie Pie then departs to a magic island, "in search of a magic flower, meets up with a king and a witch doctor and ultimately has reconciliation with Café O'Lay."