Colin Graham OBE (22 September 1931 in Hove, England – 6 April 2007 in St. Louis, Missouri) was a stage director of opera, theatre, and television.

Graham was educated at Northaw School (Hertfordshire), Stowe School and RADA. Early in his career, he began a long association with Benjamin Britten, for whom he directed all but one of the composer's stage works, including all of the world premieres after 1954. He became associated with the English Opera Group in 1953. In the 1950s, he also worked for the Royal Opera House, Covent Garden in London and later at Glyndebourne and at the English National Opera in the 1970s. In the late 1950s and early 1960s, Graham was associated with several recordings of Gilbert and Sullivan operas conducted by Sir Malcolm Sargent with the Glyndebourne Festival Chorus and principals including George Baker. He enhanced these recordings with movement for the performers that makes the recordings sound more like a live staged performance.

Graham made his American debut as a stage director at Santa Fe Opera in 1974 with his staging of Britten's Owen Wingrave. Graham later became Director of Productions for Opera Theatre of Saint Louis (OTSL) in 1978, until 1985, when he became OTSL's Artistic Director. He held this position until his death.

Graham directed the world premieres of John Corigliano's opera, The Ghosts of Versailles, for the Metropolitan Opera; The Dangerous Liaisons and André Previn's A Streetcar Named Desire for San Francisco Opera; The Song of Majnun for Lyric Opera of Chicago; and a series of three operas by Miki Minoru. In addition, he directed productions for the Santa Fe Opera, notably Bright Sheng's Madame Mao in 2003, continuing his association with general director Richard Gaddes, which had begun during the latter's tenure at OTSL. Collectively, he directed 55 world premieres of operas.